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Difference Between Vicodin and Lortab

Vicodin vs Lortab

Vicodin and Lortab are medicines that belong to a group of medicines known as narcotic pain relievers. Both of these drugs are mainly prescribed for giving relief to moderate to severe pain. Both Vicodin and Lortab contain pain-relieving agents known as hydrocodone and acetaminophen. Though these two contain the same active ingredients, there do exist some difference between the two drugs.

Vicodin and Lortab are both available in tablet form. However, Lortab is also available as a liquid elixir.

One of the main differences that can be seen between Vicodin and Lortab is in the hydrocodone and acetaminophen component. In Lortab, there may be differences in the presence of hydrocodone. However, the acetaminophen dose in Lortab remains at 500 mg irrespective of the varying hydrocodone strength.

Most of the Vicoden drug comes in 7.5 milligrams of hydrocodone and 750 milligrams of acetaminophen. The Lortab drug comes in 5 milligram, 7.5 milligram and 10 milligrams of hydrocodone and 500 milligrams of acetaminophen.

In Vicodin, the inactive ingredients include microcrystalline cellulose, colloidal silicon dioxide, starch, dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, stearic acid, and povidone. Each of the Lortab tablets contains inactive ingredients, such as, croscarmellose sodium, colloidal silicon dioxide, micro-crystalline cellulose, povidone, sugar spheres, pregelatinized starch, stearic acid, and crospovidone.

Lortab tablets are available in a pink colour and are capsule shaped. They are bisected tablets with “UCB” embossed on one side and “910” on the other side. Vicodin tablets, which also come in oval shapes or capsule shapes, are white in colour. It has “Vicodin” embossed on one side.

Summary:

1.Vicodin and Lortab are both available in tablet form. However, Lortab is also available as an liquid elixir.
2.One of the main differences that can be seen between Vicodin and Lortab is in the hydrocodone and acetaminophen components. In Lortab, there may be differences in the presence of hydrocodone whereas the acetaminophen dose in 3.Lortab remains the same.
4.Lortab tablets are available in a pink colour and are capsule shaped. Vicodin tablets, which also comes in oval shapes or capsule shapes, are white in colour.
5.Lortab are bisected tablets with “UCB” embossed on one side and “910” on the other side. Vicodin, which is also a bisected medicine, has the word “Vicodin” embossed on one side.
6.There are also certain differences in the presence of the inactive ingredients in both Vicodin and Lortab.

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5 Comments

  1. This is somewhat informative, yet there is at least one major error in your assertions vis-a-vis “Vicoden v. Lortab.”

    Quoting your page: “One of the main differences that can be seen between Vicodin and Lortab is in the hydrocodone and acetaminophen component. In Lortab, there may be differences in the presence of hydrocodone. However, the acetaminophen dose in Lortab remains at 500 mg irrespective of the varying hydrocodone strength.>>

    In fact, Lortab is not standardized at 500 mg per tablet. It has been marketed in at least three doseages of hydrocodone and acetominnophen. One can find Lortab with 10 mg Hydrocodone & 325 APAP (10/325); Lortab 10/500, 7.5/500, 5/500, and and Lortab 2.5/500 mg.

    One needs to be more careful with one’s assertion so as not to lead anyone astray.

  2. Just want to correct what appears to be an inaccuracy regarding your article about Vicodin. The most widely prescribed strength of the brand name Vicodin is Vicodin 5/500, which is 5 milligrams of hydrocodone and 500 milligrams of acetaminophen. The generic equivalent of this is of course hydrocodone/acetaminophen 5/500mg. As a practitioner I know that the 5/500 strength is prescribed much more frequently than the more potent 7.5/750mg strength, so to say or imply that most of the drug comes as the 7.5/750mg formulation based on how frequently it is prescribed is rather inaccurate or at best not well stated..

  3. S.E. Sils-Carson:

    I do not know who you are, nor what your credentials are. The following rebuttal is not for viewing by anyone else but you.

    If you would bother to read my reply above you would see that I made no reference as to how hydrocodone is compounded with acetaminophen. The quote that you attribute to me (“One of the main differences…) is actually the third paragraph of the original article by the original author, not me. My whole point and only point was to notify you that your statement in the original article, reference the first sentence in the fourth paragraph if you will, states that “Most of the Vicodin drug comes in 7.5 milligrams of hydrocodone and 750 milligrams of acetaminophen.” That statement is dead wrong by the number of prescriptions issued, period. The 5/500 combination is far, far more prescribed. For you to state that I need to be more careful about my assertations so as to not lead anyone astray is absolutely baseless and recklessly irresponsible on your part. Your demonstrated lack of ability to cognate correctly, attribute a statement to its’ proper author and admit when you are wrong without trying to generate a smokescreen basically destroys the purpose of this forum. It is not my credibility at issue here sir, but yours. Be a man and admit it, or be who you are and just go away.

  4. My comments were solely regarding the “original” piece titled “Difference Between Vocodin and Lortab,” (author unlisted). I stand by my assertion that in fact Lortab, Lorcet, and Vicodin are supplied with varying doses of both constituents. No drama or rants required.

  5. Indeed, sir, you do not know of me, nor I you. Nor do I know a thing about your erudition. I have for the first time after stumbling upon “Difference Between” and commented, for the first, and perhaps last, time solely for the sake of clarity for “Everyman.” If this is you personal fifedom, doctor, I will let your words prevail.

    Should it matter to any reader herein, I am an immunologist. I am not not a Pharm.D. – and if any of you are, you know a whole lot more than do I about the most commonly prescribed variants of the Lortab/Lorcet and all the other ubiquitous hydrocodone (or oxycodone)/acetaminophen formulations. My concern, and thus my reason for my original post here is the very real potential for APAP-induced hepatotoxicity, a very real public health problem. I see too many liver transplant candidates present due to this specific hepatotoxic issue.

    Oddly, Dr. Leshock, your blusterous, challenging assertions suggest an oddly defensive posture, yet it is hard to see why you feel the need to defend your stance. One must therefore call into question the motives behind your comments. I offered no hostility or personal challenge to you, yet it seems as though you have perceived such. Thin skin is a sign of our times in the West, but I am shocked that such an educated person would feel such a need. Am I wrong here, Dr. Leshock?

    Regardless, you are correct in your assertion that I am relatively unaware of the prescription frequency of of the various doses of Lortab/Lorcet in a given country, region, or demographic group. Apparently you are, which I do respect.

    My primary point – apparently missed by you – however, was not to contradict anyone’s knowledge about the prevalence of Lorcet/Lortab prescriptions in a given population; it was to advise the public that four grams of acetaminophen (paracetemol/APAP) is the FDA’ maximum “safe” 24 hour dosing. And further, that this dose is easily attained or exceeded given the ubiquitosity of APAP in OTC preparations. Furthermore, the 4-gram/day maximum only pertains to individuals with nominal hepatic function. while many adults do not fit this status. Given these considerations, and its desired effects, acetaminophen, is a rather worthless drug in adults; more often it is a toxic yet redily-availabe drug. APAP is chemical that would not likely gain FDA approval today due to its horrific ED/LD ratio.

    You are a clever physician, yet one must wonder why you have become agitated about my not-incorrect comments. It is often a good recommendation for one remember that science does not give a darn about beliefs and opinions. Science must follow only the data.

    Thank you,
    Steven Silz-Carson
    ssilzcar@uccs.edu

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