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Difference Between Hypo Goiter and Hyper Goiter

Hyperthyroidism is also called as an overactive thyroid (when thyroid gland makes and releases excessive thyroid hormone). Hypothyroidism is also called as an underactive thyroid (when thyroid gland does not make and release enough thyroid hormone). Hypo is more common than hyper. Though both the conditions have different symptoms, on many occasions they overlap. Goiter is associated with both Hypothyroidism and Hyperthyroidism as well. 

Goiter is a harmless (non-cancerous mostly) condition. A simple goiter may disappear or expand in size on its own. Hypothyroidism (inadequate thyroid hormone) can develop over time because of natural thyroid tissue degradation. Thyroid hormone replacement therapy can help with this.

A toxic nodular goiter can develop when a nodule manufactures thyroid hormone on its own. This can lead to hyperthyroidism (excessive thyroid hormone), which can be treated with radioactive iodine to remove the nodule.

Goiter Hypo

In Hypothyroidism, iodine deficiency leads to alleviated thyroid hormone production causing increased thyroid stimulating hormone TSH production by the pituitary gland. The elevated thyroid stimulating hormone (TSH) invigorates thyroid growth and results in goiter formation.

Hashimoto’s thyroiditis is the most common cause of hypothyroidism. When you have this sickness, your body attacks its own immune system. This attack progressively leads the thyroid to stop producing hormones, resulting in hypothyroidism. Like many autoimmune illnesses, Hashimoto’s thyroiditis affects women more than men.

Goiter Hyper

Hyperthyroidism is a medical condition in which there is excessive making up of thyroid hormone by the thyroid gland. It is also termed as overactive thyroid.

Graves’ disease is distinguished by the body’s war on itself. This attack allows the thyroid gland to produce an abnormally large amount of thyroid hormone. This autoimmune disorder is typically the underlying cause of hyperthyroidism. Graves’ disease causes your thyroid to produce an abnormally large amount of thyroid hormone.

Similarity

Both can be triggered by autoimmune diseases.

Difference between Goiter Hypo and Goiter Hyper

Definition

Goiter Hypo

In Hypothyroidism, iodine deficiency leads to alleviated thyroid hormone production causing increased thyroid stimulating hormone TSH production by the pituitary gland. The elevated thyroid stimulating hormone (TSH) invigorates thyroid growth and results in goiter formation.

Goiter Hyper

Hyperthyroidism is a medical condition in which there is excessive making up of thyroid hormone by the thyroid gland. It is also termed as overactive thyroid.

Symptoms

Goiter Hypo

  • Fatigue 
  • Dryer, irritated skin
  • Paresthesia, the sensation of having pins and needles in the hands and feet
  • Squeaky voice 
  • Constipation
  • Loss of hair
  • Moderate weight gain and weight loss challenges
  • Poor memory and concentration problems
  • Distorted hearing
  • Menorrhagia, also known as oligo- or amenorrhea
  • Dyspnea, a shortness of breath

Goiter Hyper

  • Muscle or joint pain
  • Racing heart
  • Muscle weakness
  • Increased sweating
  • Heat intolerance
  • Nails becoming less secure in their nail beds.
  • Puffy or bulging eyes
  • Short periods
  • (Urticaria) Hives

Types

Goiter Hypo

Hypothyroidism, is divided into two main types:

  • Primary Hypothyroidism – Decreased levels of thyroid hormones and elevated levels of thyroid stimulating hormone (TSH) and thyrotropin releasing hormone (TRH) – caused by:
  • Autoimmune thyroiditis
  • Thyroidectomy
  • Secondary Hypothyroidism
  • Hypothalamic failure
  • Pituitary failure
  • I-deficiency
  • Resistance of target tissues (rare)

Goiter Hyper

Diffuse toxic goiter (Graves’ disease), toxic multinodular goiter (Plummer disease), and toxic adenoma.

Treatment

Goiter Hypo

Replacement therapy by thyroxin

Goiter Hyper

  • Anti-thyroid drugs (PTU)
  • Thyroidectomy 

Summary

The points of difference between Goiter Hypo and Goiter Hyper have been summarized as below:

FAQ:

Is goiter common in hyperthyroidism or hypothyroidism?

Goiter can be associated with both hyperthyroidism and hypothyroidism

Can goiter be seen in hypothyroidism?

A goiter can occur in a gland that is producing too little hormone (hypothyroidism)

Which goiter cause hypothyroidism?

Nontoxic goiter in which thyroid is underactive causes hypothyroidism

Is Goiter a symptom of hyperthyroidism?

Goiter can become a symptom of hyperthyroidism if the thyroid gland is producing excessive hormone.

What are 3 symptoms of having a goiter?

  • swelling of neck veins
  • a growth at the base of your Adam’s apple in the front of your neck
  • hoarseness (voice grit)
  • a sense of constriction in the throat region

Is goiter and Hashimoto the same?

In the United States, Hashimoto’s thyroiditis (chronic lymphocytic thyroiditis) is a more frequent reason for Goiter development (enlarged thyroid). This autoimmune disorder (A disorder in which the body’s immune system attacks healthy cells) causes the thyroid gland to be destroyed by the sufferer’s own immune system. As the gland’s damage worsens, it can generate less thyroid hormone.

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References :


[0]Chiovato, L., Magri, F., & Carlé, A. (2019). Hypothyroidism in context: where we’ve been and where we’re going. Advances in therapy, 36, 47-58.

[1]De Leo, S., Lee, S. Y., & Braverman, L. E. (2016). Hyperthyroidism. The Lancet, 388(10047), 906-918.

[2]Gaitonde, D. Y., Rowley, K. D., & Sweeney, L. B. (2012). Hypothyroidism: an update. South African Family Practice, 54(5), 384-390.

[3]Kravets, I. (2016). Hyperthyroidism: diagnosis and treatment. American family physician, 93(5), 363-370.

[4]Image credit: https://www.canva.com/photos/MAEToSfgm1E-enlarged-thyroid-gland-diffuse-toxic-goiter-disease-endocrine-autoimmune-diseases/

[5]Image credit: https://www.canva.com/photos/MAEEDA8R334-simple-goiter-under-microscopy/

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