Difference Between 7 Keto DHEA and DHEA
“Dehydroepiandrosterone” is referred to as “DHEA.” DHEA is a hormone produced naturally by adrenal glands. DHEA also known as dehydroepiandrosterone (androstenolone), which is a steroid hormone. A metabolite product called 7-Keto DHEA (a metabolite of DHEA that is nonhormonal) is generated from the hormone DHEA. Despite having a similar structure, they have a wide range of distinct uses and characteristics.
Similarity
Both 7 Keto DHEA and DHEA are similar in structure.
7 Keto DHEA
A metabolite of DHEA (dehydroepiandrosterone (androstenolone) is 7-Keto DHEA. It is a hormone metabolite that can improve immunological performance and aid in weight loss. When DHEA (dehydroepiandrosterone (androstenolone) degrades, 7-Keto DHEA (a metabolite of DHEA that is nonhormonal) is created. It works twice as well as DHEA.
DHEA
DHEA also known as dehydroepiandrosterone (androstenolone), which is a steroid hormone. Dehydroepiandrosterone serves as a precursor (compound that participates in a chemical reaction that produces another compound) to estrogens and testosterone while aiding to elevate follicular stimulation.
Difference between 7 Keto DHEA and DHEA
Definition
7 Keto DHEA
It is a hormone secreted in the brain, reproductive organs, and the kidneys. It is metabolite product of DHEA. It has more psychological impacts than the DHEA and does not influence sex hormones
DHEA
It is secreted in the human body naturally – from the adrenal glands. It is also termed as DHEA also known as dehydroepiandrosterone (androstenolone). The chemical name is 3β-hydroxyandrost-5-en-17-one or 5-androsten-3β-ol-17-one.
Origin
7 Keto DHEA
It is a metabolite of DHEA
DHEA
It is secreted in the human body
Benefits
7 Keto DHEA
- Speed up the metabolism and heat production to encourage weight loss
- Enhances memory
- Insufficient evidence for fat burning
- Aids in cortisol reduction and heart health
- Treats PSTD in women
- Reduces alcohol intake
- Depression and thyroid function
DHEA
- Improves thinking skills in older people
- Helps in slowing down the process of aging
- Prevents erectile dysfunction
- Aids in losing weight
- Boosts immune system
- Increases muscle density in athletes
- Slows down Parkinson’s disease
- Helps in treatment of osteoporosis
- Improves mood and memory
- Helps in treating conditions like – Cervical cancer, infertility, Myalgic encephalomyelitis/Chronic Fatigue Syndrome, Rheumatoid arthritis, Crohn’s disease, Schizophrenia and sexual dysfunction
Side effects
7 Keto DHEA
It is mostly safe and non-toxic if taken for eight weeks when taken by mouth. However, some people rarely experience few minor side effects like dizziness, nausea, and low blood pressure.
DHEA
- Changes in menstrual cycle
- Facial hair in women
- Oily skin and acne
- Skin thickening
- Erratic heartbeat
- Hair loss
- Insomnia
- Stomach upset
- Headache
- High blood pressure
- Changes in cholesterol levels
- Liver damage
- Mild acneiform dermatitis
- Deepening of the voice in women
- Fatigue
Summary
The points of difference between 7 Keto DHEA and DHEA have been summarized as below:
FAQ:
Why is 7-keto-DHEA better?
In order to assist weight loss, people take 7-keto-DHEA or 7-Ketodehydroepiandrosterone, also known as 7-oxoprasterone to increase their metabolism (set of life-sustaining chemical reactions in organisms) and heat production. Additionally, 7-keto-DHEA is utilized to improve lean body mass (conflated with fat-free mass, is a component of body composition) and build muscle mass, enhance the thyroid gland’s function (a gland located beneath the larynx (voice box), the immunological system, memory, and ageing.
Can 7-keto-DHEA convert to testosterone?
No, 7-keto-DHEA (a metabolite of DHEA that is nonhormonal) does not convert to estrogen or testosterone.
Are there two types of DHEA?
Yes, DHEA – dehydroepiandosterone and its sulfate form, dehydroepiandrosterone sulfate (DHEAS).
Does 7-keto-DHEA lower cortisol?
Yes, 7-keto DHEA can lower cortisol in both men and women
What are the negative effects of 7-keto-DHEA?
- Low BP
- Hair loss
- Dizziness
- Nausea
- Liver damage
- Facial hair in women
What is the most potent DHEA?
Dehydroepiandrosterone (DHEA) is the most potent DHEA.
Why is DHEA not allowed in Canada?
DHEA is not legally sold in Canadian market and has been banned in Canada. It is identified as a controlled drug in Canada and is considered to be health risk increasing the risk of ovarian, prostate, breast cancers in males and females.
What is the downside of DHEA?
It could aggravate psychiatric disorders. DHEA could also reduce good cholesterol – high-density lipoprotein (HDL) and could also cause hirsutism which is male pattern hair growth in women.
Does DHEA make you look younger?
Yes, DHEA supplements can make you look younger by enhancing skin glow and making skin firm and hydrated. It can also reduce ageing and some age-related spots in older adults.
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References :
[0]Allolio, B., & Arlt, W. (2002). DHEA treatment: myth or reality?. Trends in Endocrinology & Metabolism, 13(7), 288-294.
[1]Jeyaprakash, N., Maeder, S., Janka, H., & Stute, P. (2022). A systematic review of the impact of 7-keto-DHEA on body weight. Archives of gynecology and obstetrics, 1-9.
[2]Martinez‐Brito, D., de la Torre, X., Colamonici, C., Curcio, D., & Botrè, F. (2019). 7‐keto‐DHEAmetabolism in humans. Pitfalls in interpreting the analytical results in the antidoping field. Drug testing and analysis, 11(11-12), 1629-1643.
[3]Rutkowski, K., Sowa, P., Rutkowska-Talipska, J., Kuryliszyn-Moskal, A., & Rutkowski, R. (2014). Dehydroepiandrosterone (DHEA): hypes and hopes. Drugs, 74, 1195-1207.
